Mexico City: One Perfect Weekend Itinerary—Where to Stay, Eat & Explore

I recently traveled to Mexico City (CDMX) for a 40th Birthday celebration, and the entire time kept thinking, what took me so long to visit this wonderful city? Not only is it a quick flight from most places in the U.S., but there was incredible food and beautiful neighborhoods with trendy shops, bars, and coffee shops on every block. I haven’t stopped raving about it since I returned. Here are my recommendations for one perfect weekend in Mexico City. This itinerary is largely based in Condesa and Roma Norte—the two neighborhoods we’d recommend to anyone visiting CDMX for the first time—with detours to Polanco, the Bazaar del Sabado in San Angel, and Xochimilco. Read our guides to Rome Norte and Condesa here.

Penthouse at Condesa DF

Friday

Check in to one of the amazing design hotels around town. We stayed at Condesa DF, a stylish boutique hotel in the quiet but trendy Condesa neighborhood. We splurged for the penthouse since it was a celebration, which had a great outdoor area and views of the city.

Casa Polanco in the Polanco neighborhood also comes highly recommended for a stylish city alternative. Casa Polanco also made the list for Best Luxury Hotels in Mexico.

Dinner: We ate at El Tigre Silencioso which was packed (in a good way) on a Friday night. With delicious cocktails and share plates this was a perfect first night dinner with friends in CDMX.

Saturday

Bazaar del Sabado(Saturday Market): Stroll around the cobble-stoned streets of the Saturday Market to shop for original art, Mexican blankets and artisanal goods.

Maximo Bistrot, one of our favorite lunch stops in Mexico City

Lunch: Maximo Bistrot

After lunch enjoy a raucous boat trip to Xochimilco, a series of town about 40 minutes from the center of the city. You can rent colorful boats and cruise around as vender boats pass by, be sure to try to street corn or buy a Mariachi serenade.

museo arte del popular in mexico city, mexico

Museums: Museo Arte del Popular, Tamayo, Jumex, Antropologia

Dinner: Contramar is a classic seafood restaurant in Mexico City.

Bar: Licoreria Limantour was recently ranked one of the Top 50 bars in the world.

SUNDAY

Breakfast: Niddo Cafe

Looking inside Niddo Cafe in the Polanco neighborhood

Art Galleries: We weren’t able to check these all out, but the ones that come highly recommended by friends who call CDMX home are Travesia Cuatro, OMR, Kurimanzuto and GAM

Lunch: Mercado Roma food hall is a great option to try a variety of foods.

bosque de chapultepec in cdmx mexico

Stroll around Bosque de Chapultepec

Snack: Churrería El Moro is a must-try for churros y chocolate. They also have multiple locations around the city.

Dinner:Maximo Bistrot

Mercado Roma food hall in Mexico City, Mexico

Mercado Roma a wonderful market/food hall.

Frequently Asked Questions

Is Mexico City safe to visit?

Yes — for travelers who stay in neighborhoods like Condesa, Roma Norte, and Polanco, Mexico City is a very safe and welcoming destination. These are well-patrolled, walkable neighborhoods popular with expats and locals alike. The same common-sense precautions you’d take in any major city apply.

What is the best neighborhood to stay in Mexico City?

Condesa and Roma Norte are the best neighborhoods for first-time visitors — walkable, full of excellent restaurants and coffee shops, and centrally located. Polanco is a good alternative if you prefer a more upscale, quieter base.

How many days do you need in Mexico City?

A long weekend (three to four days) is enough to cover the highlights — Condesa, Roma Norte, Xochimilco, the main museums, and the food scene. A full week lets you go deeper into the art galleries, day trips, and neighborhoods like Coyoacán and San Ángel.

What is the best hotel in Condesa, Mexico City?

Condesa DF is one of the best boutique hotels in the Condesa neighborhood — a beautifully designed property on a quiet tree-lined street with one of the best rooftop bars in the city.

What is Xochimilco?

Xochimilco is a network of ancient canals and floating gardens about 40 minutes south of Mexico City’s center. You rent colorful wooden boats called trajineras, vendor boats float past selling food and drinks, and mariachi bands serenade you on the water. It’s one of the most uniquely Mexican experiences in the city and a UNESCO World Heritage Site.

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